ZETA 1. is indicated for the spatial positioning and orientation of neurosurgical instruments used by surgeons. The device is indicated only for cranial surgery where reference to a rigid anatomical structure can be identified, does not require rigid fixation of the patient, and does not require fixation of a navigated instrument guide to the patient. The system is intended to be used in operating rooms and in less acute surgical settings such as interventional procedure suites. The use of the ZETA Cranial Navigation System for ventriculostomy, brain biopsy and transcranial magnetic stimulation require separate compatible instruments and accessories. ©️ 2026 ZETA Surgical Inc. All rights reserved. Unless otherwise specified, all product and service names appearing in this Internet site are trademarks owned by or licensed to ZETA Surgical, its subsidiaries or affiliates. No use of any ZETA Surgical trademark, trade name, or trade dress in this site may be made without the prior written authorization of ZETA Surgical, except to identify the product or services of the company.
REALTRACK™ Foundational Patent Published
February 1, 2026
The core of Zeta’s marker-less, real-time image guidance—built for fast setup and sub-millimetric accuracy in real clinical workflows.
"Since its foundation, our goal at ZETA SURGICAL has been to increase access to precise and safe image guidance by building navigation and robotics that can be deployed at any point of care, whether that’s a traditional OR, an ambulatory surgery center, a mental health clinic, or an emergency room.
We believe this can be transformative for patients. It enables neurosurgical procedures like biopsies to move into ASCs, allows emergency patients to receive life-saving interventions in the ER and ICU, and makes novel treatments such as robotic TMS precise and scalable in mental health clinics.
Much like a GPS finds you on a map, surgical navigation works by continuously mapping the patient and instruments during a procedure, allowing clinicians to reach internal targets accurately and minimally invasively.
I’m very excited to share the publication of this foundational patent, which reflects the core of our REALTRACK vision: an AI-driven, marker-less “GPS” for navigation and robotics, capable of being deployed in minutes with sub-millimeter accuracy at virtually any point of care.
Huge congratulations to our entire team and to our incredible clinical partners who helped make this possible."
– José María Amich, Co-Founder and CEO